Negation and lack with

The kanji functions as a marker of not, non-, and lack. In compounds it usually negates or reverses the meaning of the following element, creating words for absence, impossibility, defect, or insufficiency.

Limits and Inability

(Impossible)

不可能(ふかのう) means that doing or achieving something is completely out of reach, or describes a state where something cannot be done.

It combines 不 (not) with 可能 (possible) to show the absence of possibility.

Manga panel from 名探偵コナン showing example of Indiscriminate murder would be one thing if with 〜ならともかく.
名探偵コナン » Volume 5 » Page 110

Sonoko is invited to a band’s after party. During the get-together, the band’s singer Tatsuya eats a rice ball only to collapse and die. The police are called in, and Inspector Megure discovers the victim was poisoned. He accuses the man who prepared the food, but Conan bites into a rice ball to show it’s safe. The victim’s manager, Mari, agrees.

麻理(まり):
無差別(むさべつ)殺人(さつじん)ならともかく、たまたま達也(たつや)()べたオニギリだけに、あらかじめ(どく)仕込(しこ)むのは不可能(ふかのう)じゃありません?」
“If it were indiscriminate murder, that's one thing but since it was just the rice ball Tatsuya happened to eat, wouldn't it be impossible to poison it beforehand?”
目暮(めぐれ):
「た、(たし)かにそうだが…」
“Th-that's true.”
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Negative States

(Anxiety)

不安(ふあん) refers to a state of restlessness caused by concerns or worries that something bad might happen. It is a term often used to describe vague fears or worries without a clear object or cause.

It combines 不 (not) with (peaceful) to show a lack of ease.

Manga panel from ふらいんぐうぃっち showing example of When you're small with 〜うちは.
ふらいんぐうぃっち » Volume 5 » Page 49

During a visit with Anzu’s family, Makoto receives a request to babysit for another witch. Things are fine at first, but after a while, rain begins to pour inside. Anzu’s mother realizes that the child they’re watching over has rain magic.

杏子(あんず)(はは):
(ちい)さいうちはコントロールできないんだろうね。不安(ふあん)になると(いま)みたいに()らせちゃうんだね」
“You don't have control while you're small, right? When he's uneasy, it pours like just now.”
真琴(まこと):
「なるほど。そうですよね。いきなり()らない(ところ)じゃ心細(こころぼそ)いですよ。我慢(がまん)してたんですね」
“I see. So that's it. It's a little scary suddenly being in a place you don't know. You've been patient, haven't you?”
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(Defect)

不良(ふりょう) generally has two meanings: “of poor quality or condition” and “a person of poor character”. Depending on the context, it can refer to either a person or an object.

It combines 不 (not) with 良 (good) to show what is not good.

Manga panel from ふだつきのキョーコちゃん showing example of Thinking of revealing the truth with 〜ようと思う.
ふだつきのキョーコちゃん » Volume 3 » Page 167

Kenji thinks Kyouko is upset because he and Hikari don’t get along well.

ケンジ:
「オレは不良(ふりょう)のフリをしてるだけだってヒカリにバラそうと(おも)うんだ!!」
“I think I will reveal to Hikari that I'm just pretending to be a delinquent!”
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(Unnatural)

不自然(ふしぜん) refers to something that deviates from its original form or proper state, giving off a sense of something being off. It is often used to describe situations that feel contrived or forced, making them difficult to accept at face value.

It combines 不 (not) with 自然 (natural) to show what is not natural.

Manga panel from 名探偵コナン showing example of Only the ace of spades with 〜だけ.
名探偵コナン » Volume 12 » Page 20

The Detective Boys group visits a cabin where Professor Agasa has secretly set out clues leading to a treasure. Conan draws the group’s attention to an arrow pointing to a table, on top of which there is…

コナン:
「これまた不自然(ふしぜん)()らばったトランプの(やま)…」
“A pile of cards, rather unnaturally scattered about.”
「しかも、なぜかスペードのAだけが画鋲(がびょう)でとめてある…」
“Further, for some reason, only the ace of spades is pinned down with thumbtacks...”
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States of Uncertainty

(Mystery)

不思議(ふしぎ) refers to something that transcends human thought and understanding, something for which no reason or cause can be explained, or that is completely unpredictable.

It combines 不 (not) with 思議 (ordinary reasoning) to show something beyond easy explanation.

Manga panel from 名探偵コナン showing example of It's not like this is science fiction with 〜じゃあるまいし.
名探偵コナン » Volume 3 » Page 147

Evidence piles up for Ran that Conan, the smart young boy staying with her family, may actually be Shin’ichi, her missing childhood friend. She’s convinced that he’s Shin’ichi on the inside, but the sticking point is how he went from being a teenager to a child.

(らん):
SF(エスエフ)じゃあるまいし…」
“It's not like this is sci-fi.”
「こんな不思議(ふしぎ)(こと)ってありえない…」
“Such an incredible thing is inconceivable...”
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(Unexpected)

不意(ふい) refers to something unexpected, a sudden event, or an unforeseen situation.

It combines 不 (not) with 意 (intention) to show something outside what was intended.

Manga panel from くノ一ツバキの胸の内 showing example of Precisely because of the fundamentals with 〜からこそ.
くノ一ツバキの胸の内 » Volume 5 » Page 120

During a training session, Tsubaki quickly subdues Asagao. Sazanka uses this opportunity to launch a surprise attack, only for Tsubaki to anticipate it and take her down as well.

ツバキ:
不意(ふい)をつくばかりじゃダメです。」
“You can't rely just on surprise attacks.”
基本(きほん)があるからこそ奇襲(きしゅう)()きるんです。」
“It's precisely from having fundamentals that surprise attacks become effective.”
サザンカ:
「はい…」
“Yeah...”
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